Mechnicov Institute of Microbiology and Immunology (16K)

Immunorehabilitation Laboratory

 
Main publications
  1. Martynov A.V., Kislichenko V.S. Synthesis and properties of clathrate complexes between acylated immunoglobulins and low molecular weight substances // Pharm . J.-2004.- Vol. 2.- P.48-52
  2. Martynov A.V., Smilanskaya M.V., Peremot S.D. Studying of viral adhesia inhibitor p- carbetoxy –N-phenylaconitimid on in vovo model // Drugs.-1999.- N 3-4.- P.79-81 (Ukr)
  3. Martnov A.V., Smilanskaya M.V., Kuchma I.Yu., Peremot S.D. Antiviral activity of aconitic acid imides – new class of substances // News in pharmacy .- 1988.-Vol.2, N.18.-P.97-99 (Ukr)
  4. Martynov A.V., Kislichenko V.S., Smilanskaya M.V., Peremot S.D., Sapoznicova N.F. Studying of Ribes nigrum some extracts in anticancer effect // Clinical Pharmacy.- 1998.-Vol.2, N 3.-P.89-91
  5. Martynov A.V., Smilanskaya M.V., Peremot S.D. Studying of imides 2- and 3- carboxylic acid imides and albumines derivatives in antiviral effects // Drugs.- 2000.-N 6.-P.51-54 (Ukr)
  6. Martynov A.V., Smilanskaya M.V., Peremot S.D. Antiviral effect of polyanionic albumin in C-2 therapeutic system // Drugs.- 2002.-N 1-2.-P.39-42 (Ukr)
  7. Martynov A.V., Smilansaya M.V., Popova N.V., Kislichenko V.S., Kozuch I.O., Volkovich O.O., Tkachenko O.Yu. Studying vegetable proteoglycans and polysaccharides in therapeutic system C-2 on antiviral properties // Pharm. J.-2001.-N 4.-P.74-77 (Ukr)
  8. Martynov A.V., Chernych V.P. High-molecular weigh drugs – biotechnology products- chemical modification as instrument of precise influence on its pharmacology properties // Clin. Pharmacy.- 2002.- Vol.6, N.3.-P.3-8 (Ukr)
  9. Kovalev V.N., Martynov A.V., Krasnicova T.O., Stepanova S.I. Vegetable lectins as biological active substances for drugs development // Phys. Act.Subst.-2001.- N 1 (31).- P.74-78 (Ukr)
  10. Chernych V.P., Martynov A.V. Synthesis and biological activity of acylated tannins // Phys. Act.Subst.-2001.- N 2 (32).- P.16-19 (Ukr)
  11. Dikiy I.L., Martynov A.V. Differential – rethrotranspositional theory of cancerogenesis// News in Pharmacy.- 1997.- N 1(15).-P.88-93. (Ukr)
  12. Schemchuk L.A., Chernych V.P., Martynov A.V. Synthesis of trans-aconitic acid imides // J. Org.Chem (Rus).- 1997.-Vol.33, N 3.-P.1257-1259
  13. Martynov A.V., Smilanskaya M.V., Kozuch I.A., Volkovich O.O., Popova N.V., Kislichenko V.S. Anticancer effects of vegetable glicoproteins, that affinity to G-class immunoglobulins // Pharm. J.-2000.-N 5.-P.78-80 (Ukr)
  14. Martynov A.V., Babkin M.V., Prochoriatova E.V., Smilanskaya M.V., Peremot S.D., Gadzevich D.V., Stecenko O.V., Volkova V.V., Rudenko M.V. 1,5-pipiredil-3,7-bis (dietanolamino) – pirimidilisovalerianat for viral infection diagnostics // Ukrainian Patent # 37622 A
  15. Martyniv A.V., Smilanskaya M.V., Parchomenko A.A., Pamchenko L.A., Kuchma I.Yu., Chernych V.P., Schemchuk L.A. p-carbetoxyphenylaconitimid with antiviral properties toward vesicular stomatitis virus and herpes simplex virus // Ukrainian patent # 22189 A.
  16. Smelyanskaya M.V., Prochoriatova E.V., Babkin V.F., Panchenko L.A., Volyansky A.Yu., Chodak L.A., Martynov A.V., Pochil S.I., Kuchma I.Yu., Lisnyak Yu.V. Method of viruses detection // Ukrainian patents # 23678 A.
  17. Khaled A.Z., Zuravlev N.S., Martynov A.V. Studying of catechines and leucoantocyanidines of dock families for photodynamic anticancer activity // Pharmacom.-2002.-N 2-P.105-107
  18. Martynov A.V., Kislichenko V.S., Tkachenko O.Yu., Vinnik O.V. Technological aspects of injectable Ribes Nigrum anticancer proteoglicans // News in pharmacy.- 2002.-N 1(29).- P.33-35
  19. Martynov A.V., Chernych V.P. Synthesis and biological properties of immunoglobulins, acylated by succinia cnhydrides // News in pharmacy.- 2002.- N 3 (31).- P.13-16
  20. Litvinenko V.I., Martynov A.V., Popova N.V., Kozuch I.A. Some technological and biopharmaceutical features of Bergenia lectines extraction // Pharmacom.- 2002.-N 3.- P.18-21
  21. Martynov A.V., Chernych V.P. Drug-design and synthesis of antiviral substances – nuclear import signals inhibitors – from succinylated peptides group // News in pharmacy.- 2003.- N 1 (33).- P.3-6.
  22. Martynov A.V. Synthesis and properties of succinylated polynucleotides // News in Pharm.- 2003.-N 2(34).- P.20-23
  23. Martynov A.V., Chernych V.P. Synthesis and biological properties of vegetable proteins, succinic anhydride acylated // Drugs.-2003.-N 1-2, P.73-76
  24. Martynov A.V., Chernych V.P. Synthesis and antiproliferative properties of succinylated and aconitylated derivatives of recombinant ?-2b-interferons // Exp. Oncology. - 2003.- Vol. 25, N 4. – P. 52-54
  25. Martynov A.V. Studying of structure – activity dependence in recombinant ?-2-b- interferon succinylated derivatives // News in Pharm.-2003.-N 4 (36).-P.18-21
  26. Martynov A.V., Chernyh V.P. Features of antiviral polyanionic biopolymers exuberant negative charge definitions in its structure analysis // News in Pharm.- 2004.- N 1(37).-P.3-6
  27. Poteyko P.I., Martynov A.V., Smelyanskaya M.V., Peremot S.D., Kireev I.V. Experience of tuberculosis patients treatment with used anticytomegalovirus polyclonal immunoglobulins // Med. today and tomorrow.- 2003.-N 4.-P.88-91
  28. Martynov A.V., Smelyanskaya M.V., Kuchma I.Yu., Chernych V.P., Parchomenco A.A. ?-D- glucosammonium salt of ?-bromisovaleric acid with antiviral activity for vesicular stomatitis virus, herpes simplex virus and coronavirus // Ukrainian Patent N 23352 À.
  29. Smelyanskaya M.V., Martynov A.V. Features of used of new drug with antiviral activity – Alfavir for HCMV treatment // Vesn. Probl.of boil.and med. -1997.-Vol.14.- P.83-88
  30. Peremot S.D., Smelyanskaya M.V., Martynov A.V. Toxoplasmosis laboratory diagnostics and criteria of it examination // Vesn. Probl.of boil.and med. -1998.-Vol.23.- P.65-68
  31. Diky I.L., Martynov A.V. About question of target cancer therapy. Used of polyclonal immunoglobulins for chemeric affinotoxins receptions // Vesn. Probl.of boil.and med. -19998.- Vol.17.- P.101-107
  32. Smelyanskaya M.V., Sanina E.V., Peremot S.D., Kuchma I.Yu., Martynov A.V. Clinical and laboratory aspects of mother – child infection at the present stage // Medical news .- 1998.-N 2.- P.10-12
  33. Prochoriatova E.V., Bila N.V., Volkova V.V., Martynov A.V. Studying of infections laryngotracheitis virus and New-Castle Virus in ovo // Veterenary medicine .- 2000.-Vol.1, N 78.-P.251-255
  34. Martynov A.V., Shmatko Yu.V., Smelyanskaya M.V., Peremot S.D., Vinnik Yu.M. Detection of herpes virus type 1 antigen in lymphocytes and tumor tissue of patients with cancer of uterus // Exp. Oncology. - 2002.- Vol. 24, N 2. – P.120-122
  35. Martynov A.V., Volyanskaya N.P. Studying of alfavir medical effects in rabbits ophtalmogerpes model // Vesn. Vin. Derg.Med.Univ.-2002.- N 2.-P.311-313
  36. Marashina T.A., Psechenko N.V., Osolodchenko T.P., Martynov A.V., Paranich A.V., Savchenko S.P. Pathogenic value of antioxidant homeostasis in mice with escherichiosis // Vesn. Probl.of boil.and med. -2002.-Vol.5.- P.17-21
  37. Application for Ukrainian patent 98062886 03.06.1998 MKI 6 À 61 Ê 31/00, 6 Ñ 12 N 7/00 / Method of ointment reception for treatment of diseases, caused by intracells infections // Martynov A.V., Smilanskaya M.V., Peremot S.D., Kuchma I.Yu., Volyansky A.Yu., Mizger T.G., Dgurovich R., Dobroscok O.I.
  38. Application for Ukrainian patent 96124561 from 05.12.1996 MKI 6 À 61 Ê 31/16, Ñ 07Í 5/06 // Aconitanilic acid glucosammonium salts with anticancer activity// Martynov A.V., Chernych V.P., Smilanskaya M.V., Volyansky A.Yu., Schemcuk L.A.
  39. Application for Ukrainian patent 97105000 from 13.10.1997 MKI 6 À 61 Ê 35/14 // Methods of adoptive immunotherapy of cancer // Martynov A.V., Volyansky Yu.L., Dobroscok O.I., Kuchma I.Yu., Malcev V.I., Moskalenko V.F., Dgurovich R., Tarasov O.A.
  40. Kuchma I.Yu., Volyansky A.Yu., Moskalenko V.F., Tkachuk T.B., Dobroskok A.I., Martynov A.V., Smelyanskaya M.V., Peremot S.D. Using of cis-aconitic acid phenylimides in liposomal form for herpes treatment // J. Micr.Epid.Immunobiol.-2000.- N 5.- P.58-61
  41. Babich E.M., Kolokolova E.E., Volyansky Yu.L., Krasnopolsky Yu.M., Martynov A.V., Verezub L.G., Belozersky V.I., Sklyar N.I., Volyanskaya N.P. Studying of Bordetella Pertussis antigens liposomal form ajuvanticity with oral used // Exp. And clin.med.-2002.-N 3.-P.87-90
  42. Martynov A.V. Analysis of the low effectiveness causes of modern treatment methods of cancer mal-formations // Ann. Mech. Inst.-2002.-N 2-3.- P.57-60
  43. Method of tuberculosis patients treatment by anticytomegalovirus polyclonal immunoglobulins / Poteyko P.I., Martynov A.V., Smilyanskaya M.V., Chernyavsky V.I., Peremot S.D., Kuchma I.Yu., Bozko M.G., Nomerovchenko V.M. // MKI7 À61Ê39/00, À61Ê39/12, À61Ê39/390 Ukrainian patent N 63791 À from 63791 À, publ. . 15.01.2004., bull. N 1.
  44. Litsmanova N.V., Martynov A.V., Paranitch A.V., Svich V.A., Marishina T.A. Stability ob lipide bilayer and it laser light modification // Õ²V Int. Sc.-pract. Confer "Application of lasers in biology and medicine" 2000, may 16-19, Kharkov., P.8-9
  45. Martynov A.V., Smelyanskaya M.V. Studying of autoadopting immunoliposomal system for selective targeting of drugs to cancer cells // Resp. Sc. Conf. " Scientific directions in drug- design in Ukrainian pharmacy 2000, sept. 26-28 Kharkov.-P.61-62
  46. Litsmsnova N., Paranich A., Martynov A., Marishina T. Stability of lipid bilayer in model systems and methods of its modification/ Eur. Bioph.J.-2000.- Vol.29, N 4-5.-P.293-294.
  47. Martynov A.V., Volyanskaya N.P. Medical effect of alfavir for rabbit ophtalmoherpes treatment // Int. Sc.-Pract. Conf. "Actual questions of strategy and practical in used of antiseptics and antibiotics" 2002, sept. 11-12, Vinnitca.
  48. Martynov A.V., Kuchma I.Yu. Transposones as a factors of viruses, microorganisms and cancer cells pathogenicity // Int. Sc.Conf "Strategy and tactics in struggle wits infectious diseases" Kharkov 2001. P.12.
  49. Martynov A.V., Peremot S.D., Smelyanskaya M.V. Herpesviruses as a fector of immune reaction disbalance in cancer patients // Int. Sc.Conf. "Strategy and tactics of infectious diseases struggle" Kharkov, Oct. 23-24. 2001.-P.15-16
  50. Popova N.V., Litvinenko V.I., Martynov A.V., Volkovich O.A. Helichrisum arenarium – perspective plant // Achievements of a modern pharmaceutics and prospect of its development in a new millennium. V national congress of Ukrainian pharmacist.-Kharkov, 1999.-P.322-333
  51. Martynov A.V. Proteines and multiple protein ensemble acylation as a method for its biological activity increased // VII Int. Med.Congr. Stud. And young Sc. May 21-23, 2003.- P.256
  52. Martynov A.V., Smilyanskaya M.V., Peremot S.D. Development of b-importin nuclear import signals inhibitors – succinylated peptides – for clear of cancer cells and immunocytes from persistence herpesviruses // Oncology -2003.- Vol.5 , N 2.- P.174-175
  53. Smelyanskaya M.V., Peremot S.D., Kireev I.V., Samura B.B. Using of specific "Biopharma" immunoglobulin for antiviral immunorehabilitation of patients with herpesviral persistence // Ukr. Sc.-Pract. Conf. "Drugs for human".18/12/2003.-Kharkov. P. 143-144
  54. Smelyanskaya M.V., Martynov A.V., Peremot S.D. Substantiation of application of immunorehabilitation for patients with herpesviral persistence // Rus. Congress of doctors- infectionists.- 29-31.10.2003.- Sankt-Petersburg (Russia).- P.361
  55. Fundamental research of antiviral and anticancer drugs with targeting properties. // Report of Sc.-Res. Work.// IMI.- CFFN 42498, Gov. reg. N 0198U002478.- Kharkov., 2001.- 94 P.
  56. Development of anatoxins and somatic antigens immunifacient entheral forms for nonparentheral vaccines reception for diphtheria, meningococcus and pertussis prophylaxis // Report of Sc.-Res. Work.// IMI.- CF4.32.99, Gov. reg. N 0199U003173.- Kharkov.-2001.-142 P.
  57. Development of immunorehabilitation methods for cancer patients with herpesviral persistence.// IMI.-ÀÌS 41/2001; Gov. reg. N 0101U001117.- Kharkov., 2002.-112 p.

Research units

 
 
Microbiology units
Clinical Microbiology Laboratory
Specific Prophylactics of Drop Infection Laboratory
Viral Infections Laboratory
New and Unexplored Infection Laboratory
Antibacterial Agents Laboratory
Ecological and Epidemiological Monitoring Laboratory
Microorganisms and Mediums Biochemistry Laboratory
 
Immunology units
Immunorehabilitation Laboratory
Clinical Immunology and Allergology Laboratory
Drug-design Laboratory
Clinical Immunological Department
 
Museum of Pathogenic for People Microorganisms
 
Immunoprophylaxis and Immunorehabilitation Centre
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